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Ongoing Research

View MNSS' Ongoing Research Projects

Brain Scan

Closed Loop Deep Brain Stimulation: A mixed Methods Systematic Review

MNSS' Ongoing Research - Unpublished

Deep brain stimulation is a functional neurosurgery technique which aims to modulate brain activity by applying highly controlled electrical impulses to diseased regions of the brain. Recently, technology is shifting towards closed-loop deep brain stimulation wherein the electrical impulses delivered are modulated in real-time according to the brain’s current state. This systematic review is the first to investigate published literature which assess CL-DBS interventions with the scope of characterising patient demographic characteristics and post-operative outcomes.

LITT for Biopsy proven Radiation Necrosis: A Mixed Methods Systematic Review

MNSS' Ongoing Research - Unpublished

Laser interstitial thermap therapy (LITT) is a minimally invasive surgery consisting of the precise administration of controlled temperatures to ablate diseased brain tissue. Raditation necrosis (RN) is a type of post-radiation treatment effect (PTRE), which is increasing in incidence. In 2012, Rahmathulla et al. employed LITT to combat RN. Since then, numerous articles have been published demonstrating the efficacy and safety of this procedure. This systematic review aims to to assess the quality of reporting of published literature which investigate the use LITT for RN to while charactering reported pre-LITT patient characteristics and post-LITT outcomes.

Doctor Analyzing X-Rays
Prescription Medication

Serotonin as the link between olfactory function and depression: A Mini Review

MNSS' Ongoing Research - Unpublished

A growing body of research is increasingly demonstrating a bidirectional relationship between olfactory function and depression. Serotonin, a neurotransmitter, is controversially implicated in both olfaction and depression. This mini-review aims to assess current literature to investigate whether serotonin may be at the centre of relationship between these two disorders.

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